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Main clinical applications of MRS

With greater feasibility in the clinical practice setting, the indications for MRS are multiplying. In brain MRS, it yields diagnostic data for:

• Tumoral pathologies: choline, myo-inositol (gliomas), free lipids (necrotic tumor: glioblastoma, metastasis…), alanine (meningioma), lactate
• Demyelinizing inflammatory pathologies: myo-inositol,
• Infectious diseases: free acetate and aminoacids in certain abscesses, reduction of NAA and VIH encephalopathy
• Metabolic pathologies: myo-inositol and glutamine / glutamate in hepatic encephalopathy, lactate and diffuse cerebral distress
• Epilepsy, brain maturation and degenerative diseases…

Gliomatose cérébrale

Aside from neurology, MRS is developing in musculoskeletal radiology (muscles, bone marrow), prostate cancer imaging (citrate), breast imaging (choline and breast cancer), and liver imaging…